DNA fragment size, insert size and pre-mergingDuring the standard library preparation, we usually use physical or enzymatic methods to fragment DNA. How different fragment size...
CNV detection in capture based sequencingCopy number variations (CNVs) have been well studied regarding their association with tumorigenesis. Meanwhile, numerous targeted...
A few elusive information in BAM / SAM formatbam file may store more alignment information than you think. As probably the most important format in NGS analysis, almost all sorts of...